Publications
SNAP-tag and HaloTag fused proteins for HaSX8-inducible control over synthetic biological functions in engineered mammalian cells.
Dotson, H.L., Ngo, J.T.
Under Review.
Synthetic Mechanotransduction Using Engineered SynNotch Receptors.
Sloas, D.C., Ngo, J.T.
In Revision.
A Genetically Encodable and Chemically Disruptable System for Synthetic Post-Translational Modification Dependent Signaling.
McMahan, J.B., Marzilli, A.M., Tran, J.C., Kuffner, C.J., Ngo, J.T.
In Revision.
Engineering clinically-approved drug gated CAR circuits
Li, H,S., Wong, N.M., Tague, E.P., Ngo, J.T., Khalil, A.S., Wong, W.W.
Accepted. Cancer Cell
Precision control of intrabodies in live cells. (News and Views)
Marzilli, A.M., McMahan, J.B., Ngo, J.T.
Nature Methods, 2020, 17(3):259–260.
Split-miniSOG for Spatially Detecting Intracellular Protein-Protein Interactions by Correlated Light and Electron Microscopy.
Boassa, D., Lemieux, S.P., Lev-Ram, V., Hu, J., Xiong, Q., Phan, S., Mackey, M., Ramachandra, R., Peace, R.E., Adams, S.R., Ellisman, M.H., Ngo, J.T.
Cell Chemical Biology, 2019, 26(10):1407-1416.e5.
Chemogenetic control of gene expression and cell signaling with antiviral drugs.
Tague, E.P.*, Dotson, H.L.*, Tunney, S.N.*, Sloas, D.C., Ngo, J.T.
Nature Methods, 2018, 15(7):519-522.
PubMed Publisher Plasmids on AddGene
Commentary in Nature Methods
'Author File' in Nature Methods
Coverage in Futurity
Click-electron microscopy for imaging metabolically tagged nonprotein biomolecules.
Ngo, J.T., Adams, S.R., Deerinck, T.J., Boassa, D., Rodriguez-Rivera, F., Palida, S.K., Bertozzi, C.R., Ellisman, M.H., Tsien, R.Y.
Nature Chemical Biology, 2016, 12(6):459-65.
"Greatest Hits" in Nature Chemical Biology
Feature in Cell Chemical Biology
Feature in Angewandte Chemie
PKMζ, But Not PKCλ, Is Rapidly Synthesized and Degraded at the Neuronal Synapse.
Palida, S.F., Butko, M.T., Ngo, J.T., Mackey, M.R., Gross, L.A., Ellisman, M.H., Tsien, R.Y.
Journal of Neuroscience, 2015, 35(20):7736-7749.
Cell-specific proteomic analysis in Caenorhabditis elegans.
Yuet, K.P., Doma, M.K., Ngo, J.T., Sweredoski, M.J., Graham, R.L., Moradian, A., Hess, S., Schuman, E.M., Sternberg, P.W., Tirrell, D.A.
Proc. Natl. Acad. Sci. USA. 2015, 112(9):2705-2710.
Identification of Secreted Bacterial Proteins by Non-Canonical Amino Acid Tagging.
Mahdavi, A., Szychowski, J., Ngo, J.T., Sweredoski, M.J., Graham, R.L.J., Hess, D., Schneewind, O., Mazmanian, S.K., Tirrell, D.A.
Proc. Natl. Acad. Sci. USA. 2014, 111(1):433-438.
Mutant Methionyl-tRNA Synthetase from Bacteria Enables Site-Selective N-terminal Labeling of Proteins Expressed in Mammalian Cells.
Ngo, J.T., Schuman, E.M., Tirrell, D.A.
Proc. Natl. Acad. Sci. USA. 2013, 110(13):4992-4997
State-selective metabolic labeling of cellular proteins.
Ngo, J.T., Babin, B.M., Champion, J.A., Schuman, E.M., Tirrell, D.A.
ACS Chemical Biology, 2012, 7(8):1326-1330.
Noncanonical amino acids in the interrogation of cellular protein synthesis.
Ngo, J.T., Tirrell, D.A.
Accounts of Chemical Research, 2011, 44(9):677-685.
Cleavable biotin probes for labeling of biomolecules via azide-alkyne cycloaddition.
Szychowski, J., Mahdavi, A., Hodas, J.J., Bagert, J.D., Ngo, J.T., Landgraf, P., Dieterich D.C., Schuman, E.M., Tirrell, D.A.
J. Am. Chem. Soc. 2010, 132(51):18351-18660.
in situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons.
Dieterich, D.C., Hodas, J.J., Gouzer, G., Shadrin, I.Y., Ngo, J.T., Triller, A., Tirrell, D.A., Schuman, E.M.
Nature Neuroscience, 2010, 13(7):897-905.
Cell-selective metabolic labeling of proteins.
Ngo, J.T., Champion, J.A., Mahdavi, A., Tanrikulu, I.C., Beatty, K.E., Connor, R.E., Yoo, T.H., Dieterich, D.C., Schuman, E.M., Tirrell, D.A.
Nature Chemical Biology, 2009, 5(10):715-717.
Unnatural amino acid incorporation into virus-like particles.
Strable, E., Prasuhn, D.E. Jr., Udit, A.K., Brown, S., Link, A.J., Ngo, J.T., Lander, G., Quispe, J., Potter, C.S., Carragher, B., Tirrell, D.A., Finn, M.G.
Bioconjugate Chemistry, 2008, 19(4):866-75.