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Tension-Tuned SynNotch Receptors for Synthetic Mechanotransduction and Intercellular Force Detection
Sloas, D.C., Tran, J.C., Marzilli, A.M., Ngo, J.T. 

In press, Nature Biotechnology 

SNAP-tag and HaloTag fused proteins for HaSX8-inducible control over synthetic biological functions in engineered mammalian cells.

Dotson, H.L., Ngo, J.T. 
Under Review.


A Genetically Encodable and Chemically Disruptable System for Synthetic Post-Translational Modification Dependent Signaling.

McMahan, J.B., Marzilli, A.M., Tran, J.C., Kuffner, C.J., Ngo, J.T. 

In Revision.


Engineering clinically-approved drug gated CAR circuits

Li, H,S., Wong, N.M., Tague, E.P., Ngo, J.T., Khalil, A.S., Wong, W.W. 

Accepted. Cancer Cell


Precision control of intrabodies in live cells. (News and Views)

Marzilli, A.M., McMahan, J.B., Ngo, J.T.

Nature Methods, 2020, 17(3):259–260.


Split-miniSOG for Spatially Detecting Intracellular Protein-Protein Interactions by Correlated Light and Electron Microscopy.

Boassa, D., Lemieux, S.P., Lev-Ram, V., Hu, J., Xiong, Q., Phan, S., Mackey, M., Ramachandra, R., Peace, R.E., Adams, S.R., Ellisman, M.H., Ngo, J.T.

Cell Chemical Biology, 2019, 26(10):1407-1416.e5.  

PubMed  Publisher

Plasmids on AddGene

Commentary in Nature Methods  

Chemogenetic control of gene expression and cell signaling with antiviral drugs.

Tague, E.P.*, Dotson, H.L.*, Tunney, S.N.*, Sloas, D.C., Ngo, J.T.

Nature Methods, 2018, 15(7):519-522.  

PubMed  Publisher 
Plasmids on AddGene

Commentary in Nature Methods 
'Author File' in Nature Methods 
Coverage in Futurity

Click-electron microscopy for imaging metabolically tagged nonprotein biomolecules.

Ngo, J.T., Adams, S.R., Deerinck, T.J., Boassa, D., Rodriguez-Rivera, F., Palida, S.K., Bertozzi, C.R., Ellisman, M.H., Tsien, R.Y. 

Nature Chemical Biology, 2016, 12(6):459-65.  

PubMed  Publisher

"Greatest Hits" in Nature Chemical Biology 
Feature in Cell Chemical Biology 

Feature in Angewandte Chemie

PKMζ, But Not PKCλ, Is Rapidly Synthesized and Degraded at the Neuronal Synapse.

Palida, S.F., Butko, M.T., Ngo, J.T., Mackey, M.R., Gross, L.A., Ellisman, M.H., Tsien, R.Y.

Journal of Neuroscience, 2015, 35(20):7736-7749.

Cell-specific proteomic analysis in Caenorhabditis elegans.

Yuet, K.P., Doma, M.K., Ngo, J.T., Sweredoski, M.J., Graham, R.L., Moradian, A., Hess, S., Schuman, E.M., Sternberg, P.W., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2015, 112(9):2705-2710.

Identification of Secreted Bacterial Proteins by Non-Canonical Amino Acid Tagging.

Mahdavi, A., Szychowski, J., Ngo, J.T., Sweredoski, M.J., Graham, R.L.J., Hess, D., Schneewind, O., Mazmanian, S.K., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2014, 111(1):433-438.

Mutant Methionyl-tRNA Synthetase from Bacteria Enables Site-Selective N-terminal Labeling of Proteins Expressed in Mammalian Cells.

Ngo, J.T., Schuman, E.M., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2013, 110(13):4992-4997

State-selective metabolic labeling of cellular proteins.

Ngo, J.T., Babin, B.M., Champion, J.A., Schuman, E.M., Tirrell, D.A.

ACS Chemical Biology, 2012, 7(8):1326-1330.

Noncanonical amino acids in the interrogation of cellular protein synthesis.

Ngo, J.T., Tirrell, D.A.

Accounts of Chemical Research, 2011, 44(9):677-685.

Cleavable biotin probes for labeling of biomolecules via azide-alkyne cycloaddition.

Szychowski, J., Mahdavi, A., Hodas, J.J., Bagert, J.D., Ngo, J.T., Landgraf, P., Dieterich D.C., Schuman, E.M., Tirrell, D.A. 

J. Am. Chem. Soc. 2010, 132(51):18351-18660.

in situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons.

Dieterich, D.C., Hodas, J.J., Gouzer, G., Shadrin, I.Y., Ngo, J.T., Triller, A., Tirrell, D.A., Schuman, E.M. 

Nature Neuroscience2010, 13(7):897-905.

Cell-selective metabolic labeling of proteins.

Ngo, J.T., Champion, J.A., Mahdavi, A., Tanrikulu, I.C., Beatty, K.E., Connor, R.E., Yoo, T.H., Dieterich, D.C., Schuman, E.M., Tirrell, D.A.

Nature Chemical Biology, 2009, 5(10):715-717.

Unnatural amino acid incorporation into virus-like particles.

Strable, E., Prasuhn, D.E. Jr., Udit, A.K., Brown, S., Link, A.J., Ngo, J.T., Lander, G., Quispe, J., Potter, C.S., Carragher, B., Tirrell, D.A., Finn, M.G.
Bioconjugate Chemistry, 2008, 19(4):866-75.

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