Publications

including commentary, submitted manuscripts, and posted preprints

A Genetically Encodable and Chemically Disruptable System for Synthetic Post-Translational Modification Dependent Signaling.

McMahan, J.B., Ngo, J.T. 

In Review.

Engineering clinically-approved drug gated CAR circuits

Li, H,S., Wong, N.M., Tague, E.P., Ngo, J.T., Khalil, A.S., Wong, W.W. 

In Review.  bioxriv

Precision control of intrabodies in live cells. (News and Views)

Marzilli, A.M., McMahan, J.B., Ngo, J.T.

Nature Methods, 2020, 17(3):259–260.  Publisher

Split-miniSOG for Spatially Detecting Intracellular Protein-Protein Interactions by Correlated Light and Electron Microscopy.

Boassa, D., Lemieux, S.P., Lev-Ram, V., Hu, J., Xiong, Q., Phan, S., Mackey, M., Ramachandra, R., Peace, R.E., Adams, S.R., Ellisman, M.H., Ngo, J.T.

Cell Chemical Biology, 2019, 26(10):1407-1416.e5.  PubMed  Publisher

Chemogenetic control of gene expression and cell signaling with antiviral drugs.

Tague, E.P.*, Dotson, H.L.*, Tunney, S.N.*, Sloas, D.C., Ngo, J.T.

Nature Methods, 2018, 15(7):519-522.  PubMed  Publisher  Plasmids on AddGene

Commentary in Nature Methods  'Author File' in Nature Methods  Coverage in Futurity

Click-electron microscopy for imaging metabolically tagged nonprotein biomolecules.

Ngo, J.T., Adams, S.R., Deerinck, T.J., Boassa, D., Rodriguez-Rivera, F., Palida, S.K., Bertozzi, C.R., Ellisman, M.H., Tsien, R.Y. 

Nature Chemical Biology, 2016, 12(6):459-65.  PubMed  Publisher

"Greatest Hits" in Nature Chemical Biology  Feature in Cell Chemical Biology  Feature in Angewandte Chemie

PKMζ, But Not PKCλ, Is Rapidly Synthesized and Degraded at the Neuronal Synapse.

Palida, S.F., Butko, M.T., Ngo, J.T., Mackey, M.R., Gross, L.A., Ellisman, M.H., Tsien, R.Y.

Journal of Neuroscience, 2015, 35(20):7736-7749.

Cell-specific proteomic analysis in Caenorhabditis elegans.

Yuet, K.P., Doma, M.K., Ngo, J.T., Sweredoski, M.J., Graham, R.L., Moradian, A., Hess, S., Schuman, E.M., Sternberg, P.W., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2015, 112(9):2705-2710.

Identification of Secreted Bacterial Proteins by Non-Canonical Amino Acid Tagging.

Mahdavi, A., Szychowski, J., Ngo, J.T., Sweredoski, M.J., Graham, R.L.J., Hess, D., Schneewind, O., Mazmanian, S.K., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2014, 111(1):433-438.

Mutant Methionyl-tRNA Synthetase from Bacteria Enables Site-Selective N-terminal Labeling of Proteins Expressed in Mammalian Cells.

Ngo, J.T., Schuman, E.M., Tirrell, D.A.

Proc. Natl. Acad. Sci. USA. 2013, 110(13):4992-4997

State-selective metabolic labeling of cellular proteins.

Ngo, J.T., Babin, B.M., Champion, J.A., Schuman, E.M., Tirrell, D.A.

ACS Chemical Biology, 2012, 7(8):1326-1330.

Noncanonical amino acids in the interrogation of cellular protein synthesis.

Ngo, J.T., Tirrell, D.A.

Accounts of Chemical Research, 2011, 44(9):677-685.

Cleavable biotin probes for labeling of biomolecules via azide-alkyne cycloaddition.

Szychowski, J., Mahdavi, A., Hodas, J.J., Bagert, J.D., Ngo, J.T., Landgraf, P., Dieterich D.C., Schuman, E.M., Tirrell, D.A. 

J. Am. Chem. Soc. 2010, 132(51):18351-18660.

in situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons.

Dieterich, D.C., Hodas, J.J., Gouzer, G., Shadrin, I.Y., Ngo, J.T., Triller, A., Tirrell, D.A., Schuman, E.M. 

Nature Neuroscience2010, 13(7):897-905.

Cell-selective metabolic labeling of proteins.

Ngo, J.T., Champion, J.A., Mahdavi, A., Tanrikulu, I.C., Beatty, K.E., Connor, R.E., Yoo, T.H., Dieterich, D.C., Schuman, E.M., Tirrell, D.A.

Nature Chemical Biology, 2009, 5(10):715-717.

Unnatural amino acid incorporation into virus-like particles.

Strable, E., Prasuhn, D.E. Jr., Udit, A.K., Brown, S., Link, A.J., Ngo, J.T., Lander, G., Quispe, J., Potter, C.S., Carragher, B., Tirrell, D.A., Finn, M.G.
Bioconjugate Chemistry, 2008, 19(4):866-75.