We use protein engineering to probe and program how molecules are organized within and between cells. The goal of this work is to understand the natural mechanisms that underlie intercellular communication at cell-cell interfaces. ​Our current projects can be categorized into the following synergistic themes:

 

- Molecular Mechanobiology: how do mechanical forces influence protein & cell functions?

- Imaging the Central Dogma: when & where are proteins made, modified, & degraded? 

- New Cell Biology Tools: chemogenetic systems for visualizing & controlling protein functions.